11/10/2023 0 Comments Pickering emulsion![]() Our emulsions carrying donepezil (an anti-Alzheimer drug) showed better performance than a solution of donepezil hydrochloride in preventing memory impairment tested on laboratory mice. ![]() The reduced viscosity of pCNC-stabilized emulsions in the presence of an electrolyte, coupled with the absence of acute toxicity, allows us to recommend them as a convenient oral delivery system for fat-soluble, biologically active substances. Pickering emulsions are fine dispersions of minute droplets of two immiscible phases stabilized by solid particles adsorbed at the liquid-liquid interphase. As a consequence, the acid-base properties of the pCNC surface are practically independent of the emulsion preparation method (with or without electrolyte) as well as the concentration of the background electrolyte. Isolated soy protein (ISP) and basil seed gum (ISP-BSG) were used for the preparation of Pickering. Sketch of a Pickering emulsion and a classical (surfactant-based) emulsion. Pickering emulsion-templated was applied to produce oleogels. Therefore, the resulting aggregates are unstable and easily destroyed, even under weak mechanical stress. Pickering emulsions are emulsions of any type, either oil-in-water (o/w), water-in-oil (w/o), or even multiple, stabilized by solid particles in place of surfactants 1, 2, 3 ( Fig. This effect in pCNC-stabilized emulsions assumedly can be associated both with weak mechanical engagement between drops due to the shape of stabilizer particles and with an insignificant participation of background electrolyte cations in the formation of interdroplet interactions. Not Only a Formulation: The Effects of Pickering Emulsion on the Entomopathogenic Action of Metarhizium brunneum. From: Coordination Chemistry Reviews, 2022. The viscosity of pCNC-stabilized emulsions tends to decrease with increasing electrolyte concentration in the system, which is not characteristic of rod-like CNC-stabilized emulsions. In general, the pickering emulsion method can produce a double unique chemical environment for solid nanoparticles, so the selective modification process is very advantageous for preparing of Janus nanoparticles. Plate-like cellulose nanocrystals at a concentration of 16 g/L are able to form delamination-resistant emulsions without added electrolytes. A significant influence of the shape of nanoparticles (compared to the classical rod-like shape) on the stability parameters and rheological characteristics of emulsions is shown. ![]() Effects of storage, pCNC concentration, and NaCl on the stability and properties of Pickering emulsions, including the creaming index, droplet size, zeta potential, acid-base surface properties, and rheology, were studied. In this work, we studied for the first time the formation of olive oil emulsions in water stabilized by plate-like nanocrystals with the supramolecular structure of cellulose II (pCNC). In the pharmaceutical field, Pickering emulsions are considered suitable for topical administration to the skin and mucosal surfaces of the body as well as for oral administration 2, 10 Different particles are used to stabilise Pickering emulsions, including those of inorganic origin like clay, hydroxyapatite, magnesium hydroxide, magnetic ir. ![]()
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